Research

CCCZ Lighthouse Project

CANCER-Microbiome – Unravel the power of the microbiome as a novel precision oncology approach

Inflammation

Intestinal Inflammation Research, Department of Gastroenterology and Hepatology University Hospital Zurich

The impact of Nano- and Microparticles on intestinal homeostasis

Identify novel therapeutic targets for the treatment of Crohn's disease associated fistula

The role of GB96 in the intestinal epithelium

Elucidating the role for PTPN2 in chronic inflammatory liver diseases

PTPN2 activation as a novel therapeutic target for the treatment of IBD

The role of epithelial cells differentiation in the pathogenesis of celiac disease

Microbiome

Microbiome Research, Department of Gastroenterology and Hepatology University Hospital Zurich

Selected clostridiales bacterias as novel treatment for solid tumors

Unravelling the mechanism behind the anti-tumor effect of commensal gut microbs in solid tumors

Impact of the intestinal microbiome on colorectal cancer metastasis

Cancer

Colorectal cancer research, Department of Gastroenterology and Hepatology University Hospital Zurich

The role of SKAP2 in inflammatory bowel diseases and colorectal cancer

The role of PTPN23 in the development of colorectal cancer

Unravelling the role for PTPN2 in the pathogenesis of colorectal carcinoma

Effect of integrin αvβ6 on TGF-β signaling, anit-tumor immune response and tumor growth in colorectal cancer

Personalizing checkpoint inhibitor therapy in melanoma patients by defining predictive factors and therapeutic approaches for the treatment of immune-mediated colitis.

Our research is supported by grants awarded by the following institutions: